Oh yeah...*facepalms* He would work with the Vovoides under that principle of 'Keep your friends close, and your enemies closer.'
Well, uh, you guys kind of all work for the Tzimisce vovoides in general, and your sire would be closely allied with the vovoides, and if you didn't have connections with the vovoides you wouldn't be a Prince - because non-vovoide approved princes only exist if they have the protection of something epic, or if they're incredibly powerful and fearsome in their own regard - like Basilio, who conquered Sofia with the help of an alliance he made with the Tzimisce vovoides who were afraid of Gabor and the Dacian, and with Noriz (a notorious Diablerist and sire to probably half the Tzimisce in Transylvania), held it with the authority of Constantinople and Michael, and protected it with his crew of elder ghouls, his personal retinue, his childer (whose reputations he built up), and his own reputation as a pre-eminent Abyss Mystic and powerful, influential Lasombra.
There are also some select other princes that hold it based on power and sires alone - like the Prince of Buda-Pest Vencel Rikard, who holds Buda-Pest because of his sire Bulscu, a legendary depraved and powerful Methuselah known for his betrayal of the Brujah to the Ventrue (he was one of those personally responsible for shattering Carthage).
Kiril only holds Sofia because of Boukephos' blessing and Basilio's support.
Steeple only holds Tihuta Pass by Radu's good grace
Lucien only holds his (extremely extensive) lands because he has destroyed Sandor and assumed his identity.
If Steeple's close connections to the Tremere were revealed, he would lose Tihuta Pass and be made an enemy of the Tzimisce. If he would fail to escape he'd be taken in, his ghouls and servants would be destroyed, and he would be tortured for information and then eventually turned into a Vozhd's toilet.
If Lucien was discovered then literally every Koldun in Transylvania except for Yorak would join together in an effort to destroy him (likely reducing half of Transylvania to ash in the process).
If it wasn't for Basilio's strength and the Dacian's reputation (Basilio having consumed the Dacian), Kiril would just go to sleep one morning and never wake up.
Basically, you can't
really be an enemy of the vovoides. I mean, you can, but if you ever take any action against them and it's linked back to you, then it doesn't really end well. So, not really any point in making an enemy of the vovoides when most of the story is you helping them (and yourself, since you share the same goals).